Regular Article THROMBOSIS AND HEMOSTASIS Regulatory T cells are strong promoters of acute ischemic stroke in mice by inducing dysfunction of the cerebral microvasculature
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چکیده
*Christoph Kleinschnitz,1 *Peter Kraft,1 Angela Dreykluft,1 Ina Hagedorn,2 Kerstin Göbel,3 Michael K. Schuhmann,3 Friederike Langhauser,1 Xavier Helluy,4 Tobias Schwarz,1 Stefan Bittner,3 Christian T. Mayer,5 Marc Brede,6 Csanad Varallyay,7 Mirko Pham,8 Martin Bendszus,8 Peter Jakob,4 Tim Magnus,9 Sven G. Meuth,3,10 Yoichiro Iwakura,11 Alma Zernecke,2 Tim Sparwasser,5 Bernhard Nieswandt,2 Guido Stoll,1 and Heinz Wiendl3
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Ischemic stroke accounts for about 87 percent of all cases. It occurs as a result of an obstruction within a vessel of the brain and sudden loss of blood circulation to the corresponding area resulting in the loss of brain function. It is caused by thrombotic or embolic occlusion of an artery and is more common than hemorrhagic stroke. We know that most of the injuries after an acute ischemic s...
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